Molecular Formula | C5H4ClN5 |
Molar Mass | 169.57 |
Density | 2.09±0.1 g/cm3(Predicted) |
Boling Point | 282.3±50.0 °C(Predicted) |
pKa | 9.35±0.20(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
UN IDs | UN2811 |
Use | 4-chloro-1h-pyrazolo [3,4-D] pyrimidin-6-amine is a pyrimidine derivative and is useful as a pharmaceutical intermediate. |
preparation | pyrazolo [3,4-d] Pyrimidine structure synthesis method is more, the pyrazolo [3,4-d] pyrimidine derivative can be synthesized using the pyrazole ring as a parent ring or the pyrazolo [3,4-d] pyrimidine derivative can be synthesized using the pyrimidine ring as a parent ring. With 2-amino -4, 6-dichloropyrimidine-5-carbaldehyde as starting material, 4-chloro-1h-pyrazolo [3,4-D] pyrimidin-6-amine. The synthesis reaction formula is shown below: Fig. 1 The synthesis reaction formula of 4-chloro-1h-pyrazolo [3,4-D] pyrimidin-6-amine |